Radioiodine treatment for non-toxic goitre

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Radioiodine treatment for non-toxic goitre

There is no ideal treatment for benign multinodular goitre. Besides surgery, which is recommended for large goitres or when malignancy cannot be excluded, the non-surgical treatment options are levothyroxine therapy and radioiodine ((131)I) therapy. Conventional (131)I therapy [without recombinant human thyroid-stimulating hormone (rhTSH)] has been used for more than a decade in symptomatic non...

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Radioiodine treatment of multinodular non-toxic goitre.

OBJECTIVE To investigate the long term effect of radioactive iodine on thyroid function and size in patients with non-toxic multinodular goitre. DESIGN Consecutive patients with multinodular non-toxic goitre selected for radioactive iodine treatment and followed for a minimum of 12 months (median 48 months) after an intended dose of 3.7 MBq/g thyroid tissue corrected to a 100% uptake of iodin...

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Parathyroid gland function after radioiodine ((131)I) therapy for toxic and non-toxic goitre.

INTRODUCTION The therapeutic effect of radioactive iodine ((131)I) on benign goitre consists of the emission of tissue-destructive beta-radiation. Since the range of beta (131)I radiation in tissue can reach 2.4 mm, it can affect the adjacent parathyroid glands. The purpose of this paper is to assess parathyroid function in patients with toxic and non-toxic goitres, up to five years following (...

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Takotsubo cardiomyopathy following radioiodine therapy for toxic multinodular goitre.

We report on a 73-year-old man with a toxic multinodular goitre, which was treated with radioiodine therapy (I-131) without pretreatment with an antithyroid drug. Four weeks later he presented with rapidly progressive dyspnoea and a significant increase in free thyroxin. The electrocardiogram showed ST -segment elevation, and echocardiography demonstrated apical akinesia and a left ventricular ...

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Non-toxic Goitre in Males.

Occult bleeding from the gastro-intestinal tract for which no cause can be found is not uncommon in cases of iron-deficiency anaemia. A follow-up study of 68 patients in whom this diagnosis was made after initial investigation has revealed only 17 in whom some cause of bleeding became apparent (in 12 aspirin ingestion, in two bleeding piles, in one a gastric ulcer, in one a possible carcinoma o...

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ژورنال

عنوان ژورنال: F1000 Medicine Reports

سال: 2009

ISSN: 1757-5931

DOI: 10.3410/m1-70